Steroidal Sapogenins in Amazonian Plants

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Preliminary pharmacobiological study of new steroidal sapogenins.

The chemotherapeutic study of a limited series of steroidal sapogenins from several endemic species of the flora of the Canary Islands is presented here. On the whole, they possess a very weak antibacterial activity, a slight antifungal effect and one of them, vespertilin, displays interesting cytostatic activity (ID50 = 5 micrograms/ml). A pharmacodynamic screening carried out on this product ...

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Antimicrobial activity of amazonian medicinal plants

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De novo Transcriptome Assembly and the Putative Biosynthetic Pathway of Steroidal Sapogenins of Dioscorea composita

The plant Dioscorea composita has important applications in the medical and energy industries, and can be used for the extraction of steroidal sapogenins (important raw materials for the synthesis of steroidal drugs) and bioethanol production. However, little is known at the genetic level about how sapogenins are biosynthesized in this plant. Using Illumina deep sequencing, 62,341 unigenes were...

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ژورنال

عنوان ژورنال: Nature

سال: 1954

ISSN: 0028-0836,1476-4687

DOI: 10.1038/1731098a0